Attenuated Retrovirus Vaccines and AIDS

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Attenuated retrovirus vaccines and AIDS.

(1995). outlined by K. Sheehan et al. [J. Immunol. 142, 3884 splenocytes by culture with MulL-12 (10 U/ml Hoff4. S. Hemmi, R. Bohni, G. Stark, Cell 76, 803 (1994); J. (1989)]. 1 G5, 1 Fl, and 2E2 are hamster mAbs spemann-La Roche, Nutley, NJ) and MuIL-4 mAb Soh et a/., ibid., p. 793; S. A. Marsters, D. Pennica, E. cific for the MuIFN-y receptor (x chain. The MuIFN--y (1 1 B1 1) (10 ,ug/ml, DNAX...

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Isolation of an infectious endogenous retrovirus in a proportion of live attenuated vaccines for pets.

The genomes of all animal species are colonized by endogenous retroviruses (ERVs). Although most ERVs have accumulated defects that render them incapable of replication, fully infectious ERVs have been identified in various mammals. In this study, we isolated a feline infectious ERV (RD-114) in a proportion of live attenuated vaccines for pets. Isolation of RD-114 was made in two independent la...

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Live Attenuated Measles Mumps and Rubella Vaccines:

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Strategies for AIDS vaccines.

In the global AIDS epidemic, over half of all infections have occurred in people less than 25 years old resulting in profound social, economic and demographic consequences. Current estimates indicate that the present 15 million HIV infections will increase to over 30 million by the end of the millennium. For most countries a safe and effective vaccine offers the only hope of controlling the spr...

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Aids-associated Retrovirus from Mother to Infant

or bisexuals, intravenous drug abusers, recipients of blood and blood products, Haitians, and the heterosexual partners of individuals in these groups.4-7 Affected infants, who account for about 1% of cases of AIDS, have usually been born to women in these at-risk groups. A smaller number of infants seem to have acquired the disease from blood transfusions.9 Where the mother has been the appare...

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ژورنال

عنوان ژورنال: Science

سال: 1995

ISSN: 0036-8075,1095-9203

DOI: 10.1126/science.270.5239.1218